Youngsook Shin
Olive View-UCLA Medical Center(US)
Publications by Year
Research Areas
Carbohydrate Chemistry and Synthesis, Glycosylation and Glycoproteins Research, PI3K/AKT/mTOR signaling in cancer, Chronic Lymphocytic Leukemia Research, Cytokine Signaling Pathways and Interactions
Most-Cited Works
- → Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors(2019)691 cited
- → Fmoc-Based Synthesis of Peptide-αThioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation(1999)363 cited
- → Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)acetamides as Covalent Inhibitors of KRASG12C(2019)103 cited
- → Discovery and in Vivo Evaluation of (S)-N-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and Related PI3Kδ Inhibitors for Inflammation and Autoimmune Disease(2014)85 cited
- → Synthesis of Oxime-Linked Mucin Mimics Containing the Tumor-Related TN and Sialyl TN Antigens(2001)77 cited
- → Inhibiting NF-κB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure–activity relationship, and co-crystal structures(2013)71 cited
- → Discovery and in Vivo Evaluation of Dual PI3Kβ/δ Inhibitors(2012)49 cited
- → Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3Kδ Inhibitors(2015)34 cited
- → Discovery of [1,2,4]Triazolo[1,5-a]pyridine Derivatives as Potent and Orally Bioavailable RORγt Inverse Agonists(2020)24 cited
- → Synthesis and SAR study of potent and selective PI3Kδ inhibitors(2015)24 cited