Huan‐Chieh Chien
Amgen (United States)(US)
Publications by Year
Research Areas
Drug Transport and Resistance Mechanisms, Amino Acid Enzymes and Metabolism, Metabolism and Genetic Disorders, Epigenetics and DNA Methylation, Pharmacogenetics and Drug Metabolism
Most-Cited Works
- → OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin(2014)235 cited
- → Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin(2016)226 cited
- → Metformin Is a Substrate and Inhibitor of the Human Thiamine Transporter, THTR-2 (SLC19A3)(2015)108 cited
- → Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1)(2018)77 cited
- → A placental growth factor is silenced in mouse embryos by the zinc finger protein ZFP568(2017)69 cited
- → Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1)(2017)64 cited
- → Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content(2018)63 cited
- → Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives(2020)58 cited
- → Cardiac contraction and relaxation are regulated by distinct subcellular cAMP pools(2023)48 cited
- → Prediction and validation of enzyme and transporter off-targets for metformin(2015)47 cited