Keshab Sarma
Sathyabama Institute of Science and Technology(IN)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, Asymmetric Synthesis and Catalysis, Chemical Synthesis and Analysis, Biochemical and Molecular Research, Hepatitis C virus research
Most-Cited Works
- → The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture(2005)215 cited
- → Structure-Based Drug Design of RN486, a Potent and Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis(2014)107 cited
- → Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479(2007)96 cited
- → Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as Orally Bioavailable and Highly Selective Inhibitors of p38α Mitogen-Activated Protein Kinase(2011)74 cited
- → Stabilization energy of polyenyl radicals: all-trans-nonatetraenyl radical by thermal rearrangement of a semirigid {4-1-2} heptaene. Model for thermal lability of .beta.-carotene(1992)41 cited
- → Perturbation of the Degenerate, Concerted Cope Rearrangement by Two Phenyl Groups in Active Positions of (E)-1,4-Diphenylhexa-1,5-diene. Acceleration by High Pressure as Criterion of Cyclic Transition States(1994)41 cited
- → Physicochemical Properties of the Nucleoside Prodrug R1626 Leading to High Oral Bioavailability(2008)36 cited
- → Finding the perfect spot for fluorine: Improving potency up to 40-fold during a rational fluorine scan of a Bruton’s Tyrosine Kinase (BTK) inhibitor scaffold(2014)33 cited
- → A Non-Cope among the Cope Rearrangements of 1,3,4,6-Tetraphenylhexa-1,5-dienes(1999)29 cited
- → Diphenyl Ether Non‐Nucleoside Reverse Transcriptase Inhibitors with Excellent Potency Against Resistant Mutant Viruses and Promising Pharmacokinetic Properties(2008)27 cited