Patrick Barton
UCB Pharma (United Kingdom)(GB)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Computational Drug Discovery Methods, Analytical Chemistry and Chromatography, Drug Transport and Resistance Mechanisms, Enzyme Catalysis and Immobilization
Most-Cited Works
- → A Comparison of Physiochemical Property Profiles of Development and Marketed Oral Drugs(2003)533 cited
- → The Influence of Nonspecific Microsomal Binding on Apparent Intrinsic Clearance, and Its Prediction from Physicochemical Properties(2002)403 cited
- → From ATP to AZD6140: The discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis(2007)233 cited
- → THE BINDING OF DRUGS TO HEPATOCYTES AND ITS RELATIONSHIP TO PHYSICOCHEMICAL PROPERTIES(2004)171 cited
- → Estimating human ADME properties, pharmacokinetic parameters and likely clinical dose in drug discovery(2019)129 cited
- → Application of In Silico, In Vitro and Preclinical Pharmacokinetic Data for the Effective and Efficient Prediction of Human Pharmacokinetics(2012)76 cited
- → A Rapid Computational Filter for Cytochrome P450 1A2 Inhibition Potential of Compound Libraries(2005)73 cited
- → Transmembrane Signalling(2002)70 cited
- → A Method for Measuring the Lipophilicity of Compounds in Mixtures of 10(2011)70 cited
- → QSAR and the Rational Design of Long-Acting Dual D2-Receptor/β2-Adrenoceptor Agonists(2003)63 cited