Federico Bernal
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, Cancer-related Molecular Pathways, Marine Toxins and Detection Methods, Lymphoma Diagnosis and Treatment, Marine Sponges and Natural Products
Most-Cited Works
- → Reactivation of the p53 Tumor Suppressor Pathway by a Stapled p53 Peptide(2007)553 cited
- → MDM4 is a key therapeutic target in cutaneous melanoma(2012)303 cited
- → A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53(2010)285 cited
- → Essential Role of the Linear Ubiquitin Chain Assembly Complex in Lymphoma Revealed by Rare Germline Polymorphisms(2014)141 cited
- → Total Synthesis of the Proposed Azaspiracid‐1 Structure, Part 1: Construction of the Enantiomerically Pure C1–C20, C21–C27, and C28–C40 Fragments(2003)102 cited
- → Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization(2018)97 cited
- → Chapter 22 Synthesis and Biophysical Characterization of Stabilized α‐Helices of BCL‐2 Domains(2008)95 cited
- → Total Synthesis and Structural Elucidation of Azaspiracid-1. Construction of Key Building Blocks for Originally Proposed Structure(2006)71 cited
- → Synthesis of the FGHI Ring System of Azaspiracid(2001)65 cited
- → Synthesis of the ABCD Ring System of Azaspiracid We thank Drs. D. H. Huang and G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. This work was financially supported by the National Institutes of Health (USA), The Skaggs Institute for Chemical Biology, a predoctoral fellowship from Bristol-Myers Squibb (to F.B.), postdoctoral fellowships from The Skaggs Institute for Research (to W.Q.), the Academy of Finland, the Ella and Georg Ehrnrooth Foundation and the Tauno Tönning Foundation (all to P.M.P.), and Bayer AG (to J.H.), as well as grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-La Roche, DuPont, Merck, Novartis, Pfizer, and Schering Plough.(2001)60 cited