Sabine Schultes
Boehringer Ingelheim (Austria)(AT)Vrije Universiteit Amsterdam(NL)
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Computational Drug Discovery Methods, Chemical Synthesis and Analysis, Mast cells and histamine, Protein Structure and Dynamics
Most-Cited Works
- → Ligand efficiency as a guide in fragment hit selection and optimization(2010)244 cited
- → Detailed analysis of biased histamineH4receptor signalling byJNJ7777120 analogues(2013)39 cited
- → Design and pharmacological characterization of VUF14480, a covalent partial agonist that interacts with cysteine 983.36 of the human histamine H4 receptor(2013)32 cited
- → A medicinal chemistry perspective on melting point: matched molecular pair analysis of the effects of simple descriptors on the melting point of drug-like compounds(2012)27 cited
- → Mapping histamine H4receptor–ligand binding modes(2012)26 cited
- → Combinatorial Consensus Scoring for Ligand-Based Virtual Fragment Screening: A Comparative Case Study for Serotonin 5-HT3A, Histamine H1, and Histamine H4Receptors(2015)18 cited
- → Bispyrimidines as Potent Histamine H4 Receptor Ligands: Delineation of Structure–Activity Relationships and Detailed H4 Receptor Binding Mode(2013)11 cited
- → Combining Quantum Mechanical Ligand Conformation Analysis and Protein Modeling to Elucidate GPCR–Ligand Binding Modes(2012)9 cited
- Computational Medicinal Chemistry in Drug Discovery(2013)