Linda O. Elliott
Publications by Year
Research Areas
Cell death mechanisms and regulation, Synthesis and biological activity, Ubiquitin and proteasome pathways, Synthesis and Characterization of Heterocyclic Compounds, Computational Drug Discovery Methods
Most-Cited Works
- → IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis(2007)1,198 cited
- → Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)(2012)247 cited
- → Design, Synthesis, and Biological Activity of a Potent Smac Mimetic That Sensitizes Cancer Cells to Apoptosis by Antagonizing IAPs(2006)174 cited
- → Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP(2004)133 cited
- → Antagonism of c-IAP and XIAP Proteins Is Required for Efficient Induction of Cell Death by Small-Molecule IAP Antagonists(2009)95 cited
- → Structure and Function Analysis of Peptide Antagonists of Melanoma Inhibitor of Apoptosis (ML-IAP)(2003)93 cited
- → A Selective, Slow Binding Inhibitor of Factor VIIa Binds to a Nonstandard Active Site Conformation and Attenuates Thrombus Formation in Vivo(2005)41 cited
- → Orally Bioavailable Antagonists of Inhibitor of Apoptosis Proteins Based on an Azabicyclooctane Scaffold(2009)38 cited
- → Antagonists of inhibitor of apoptosis proteins based on thiazole amide isosteres(2010)21 cited
- → Evaluation of Assay Technologies for the Identification of Protein–Peptide Interaction Antagonists(2007)17 cited