Alexander Hillisch
Rohde & Schwarz (Germany)(DE)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Estrogen and related hormone effects, DNA and Nucleic Acid Chemistry, RNA and protein synthesis mechanisms, Hormonal Regulation and Hypertension
Most-Cited Works
- → Utility of homology models in the drug discovery process(2004)311 cited
- → Discovery of BAY 94‐8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases(2012)259 cited
- → Bayer’s in silico ADMET platform: a journey of machine learning over the past two decades(2020)208 cited
- → Recent advances in FRET: distance determination in protein–DNA complexes(2001)191 cited
- → A New Mode of Mineralocorticoid Receptor Antagonism by a Potent and Selective Nonsteroidal Molecule(2010)185 cited
- → Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1(2015)176 cited
- → The Lab Oddity Prevails: Discovery of Pan‐CDK Inhibitor (R)‐S‐Cyclopropyl‐S‐(4‐{[4‐{[(1R,2R)‐2‐hydroxy‐1‐methylpropyl]oxy}‐5‐(trifluoromethyl)pyrimidin‐2‐yl]amino}phenyl)sulfoximide (BAY 1000394) for the Treatment of Cancer(2013)174 cited
- → Binding Free Energy Calculations for Lead Optimization: Assessment of Their Accuracy in an Industrial Drug Design Context(2014)172 cited
- → Dissecting Physiological Roles of Estrogen Receptor α and β with Potent Selective Ligands from Structure-Based Design(2004)169 cited
- → Improving the hit-to-lead process: data-driven assessment of drug-like and lead-like screening hits(2006)151 cited