Frederick Cohen
Nurix (United States)(US)
Publications by Year
Research Areas
Marine Sponges and Natural Products, Ubiquitin and proteasome pathways, Cell death mechanisms and regulation, Chemical Synthesis and Analysis, CAR-T cell therapy research
Most-Cited Works
- → USP7 small-molecule inhibitors interfere with ubiquitin binding(2017)334 cited
- → Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)(2012)247 cited
- → Enantioselective Total Synthesis of Batzelladine F: Structural Revision and Stereochemical Definition(2001)87 cited
- → Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton’s Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies(2024)87 cited
- → Discovery of Dual Leucine Zipper Kinase (DLK, MAP3K12) Inhibitors with Activity in Neurodegeneration Models(2014)86 cited
- → Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques(2017)86 cited
- → Depletion of CD8+ cells in human thymic medulla results in selective immune deficiency.(1989)76 cited
- → Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety(2019)75 cited
- → Estrogen Production and Its Origin in Men with Gonadotropin-Producing Neoplasms*(1974)65 cited
- → Guanidine alkaloid analogs as inhibitors of HIV-1 Nef interactions with p53, actin, and p56 lck(2004)64 cited