Deborah S. Malley
University of Cambridge(GB)Addenbrooke's Hospital(GB)
Publications by Year
Research Areas
Glioma Diagnosis and Treatment, Epigenetics and DNA Methylation, MicroRNA in disease regulation, Cancer, Hypoxia, and Metabolism, Neurofibromatosis and Schwannoma Cases
Most-Cited Works
- → A distinct region of the MGMT CpG island critical for transcriptional regulation is preferentially methylated in glioblastoma cells and xenografts(2011)162 cited
- → MGMT CpG island is invariably methylated in adult astrocytic and oligodendroglial tumors with IDH1 or IDH2 mutations(2011)84 cited
- → Adult grade II diffuse astrocytomas are genetically distinct from and more aggressive than their paediatric counterparts(2011)53 cited
- → CpG island hypermethylation of the neurofibromatosis type 2 (NF2) gene is rare in sporadic vestibular schwannomas(2010)26 cited
- → Abstract 2794: Mutation of IDH1/2 is strongly associated with MGMT methylation in adult astrocytic and oligodendroglial tumors(2011)
- → Abstract LB-181: Genome-wide DNA methylation analysis reveals novel hypermethylated genes in astrocytic tumors(2011)