Dhruv Bole
Rapt Therapeutics (United States)(US)
Publications by Year
Research Areas
Virus-based gene therapy research, Ultrasound and Hyperthermia Applications, Inflammatory mediators and NSAID effects, Viral gastroenteritis research and epidemiology, Ferroptosis and cancer prognosis
Most-Cited Works
- → Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition(2017)1,673 cited
- → Neuron-targeted gene therapy rescues multiple phenotypes of STXBP1-related disorders in mice and is well tolerated in nonhuman primates(2025)2 cited
- → Abstract 1006: Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition(2017)2 cited
- → Engineering Non-Viral Gene Therapy Vector for Simultaneous Transgenic FVIII Protein Expression from Liver Sinusoidal Endothelial Cells (LSECs) and Hepatocytes upon Non-Invasive Transcutaneous Ultrasound-Mediated Gene Delivery(2024)
- → Abstract B098: GPX4 is a broadly shared gene vulnerability among residual tumors(2018)
- → Development of a Nonviral Gene Therapy for X-linked Alport Syndrome by Targeted Transcutaneous Ultrasound-Mediated Gene Delivery(2024)
- → Engineering FVIII Protein for Enhancing Expression and Secretion Profile to Achieve Normal Level of FVIII in Plasma Utilizing Noninvasive Transcutaneous Ultrasound Mediated Gene Delivery(2024)
- → Kidney-Targeted Delivery of Nonviral Nucleic Acids Using Noninvasive Transcutaneous Ultrasound Enables Safe, Re-dosable, Titratable, and Durable Gene Expression in Mice and Nonhuman Primates(2024)
- → Targeted Non-Viral Gene Delivery through Transcutaneous Ultrasound Enables Robust, Redosable, Titratable, and Durable FVIII and FIX Gene Expression in the Liver in Murine Models(2024)
- → Development of a Nonviral Genetic Medicine for ADPKD Administered through Targeted Transcutaneous Ultrasound-Mediated Delivery(2024)