David J. Gallacher
University Hospital of Wales(GB)
Publications by Year
Research Areas
Cardiac electrophysiology and arrhythmias, Ion channel regulation and function, Neuroscience and Neural Engineering, Receptor Mechanisms and Signaling, Neuroscience and Neuropharmacology Research
Most-Cited Works
- → Predicting drug‐induced changes in QT interval and arrhythmias: QT‐shortening drugs point to gaps in the ICHS7B Guidelines(2008)130 cited
- → A new biomarker – index of Cardiac Electrophysiological Balance (iCEB) – plays an important role in drug-induced cardiac arrhythmias: beyond QT-prolongation and Torsades de Pointes (TdPs)(2013)126 cited
- → Common respiratory conditions of the newborn(2016)126 cited
- → Evaluation of Index of Cardio‐Electrophysiological Balance (iCEB) as a New Biomarker for the Identification of Patients at Increased Arrhythmic Risk(2015)115 cited
- → In vivo mechanisms precipitating torsades de pointes in a canine model of drug-induced long-QT1 syndrome(2007)113 cited
- → Best practice in the conduct of key nonclinical cardiovascular assessments in drug development: Current recommendations from the Safety Pharmacology Society(2011)103 cited
- → Time for a Fully Integrated Nonclinical–Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective(2020)94 cited
- → Anatomic variation of the middle cerebral artery in the Sprague-Dawley rat.(1993)84 cited
- → The effect of changes in core body temperature on the QT interval in beagle dogs: a previously ignored phenomenon, with a method for correction(2008)80 cited
- → A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate(2017)73 cited