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Patrick Smith | doi.page

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Patrick Smith

National Institute of Allergy and Infectious Diseases(US)UK Astronomy Technology Centre(GB)

Publications by Year

Research Areas

Adenosine and Purinergic Signaling, Monoclonal and Polyclonal Antibodies Research, Immune Cell Function and Interaction, Inflammasome and immune disorders, interferon and immune responses

Most-Cited Works

→ A2A adenosine receptor protects tumors from antitumor T cells(2006)1,022 cited
→ Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor(2012)551 cited
→ The staufen/pumilio Pathway Is Involved in Drosophila Long-Term Memory(2003)463 cited
→ Mouse model recapitulating human Fcγ receptor structural and functional diversity(2012)304 cited
→ Oxygenation Inhibits the Physiological Tissue-Protecting Mechanism and Thereby Exacerbates Acute Inflammatory Lung Injury(2005)285 cited
→ FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo(2010)193 cited

→ Targeted Deletion of HIF-1α Gene in T Cells Prevents their Inhibition in Hypoxic Inflamed Tissues and Improves Septic Mice Survival(2007)

172 cited

→ Siglecs-7/9 function as inhibitory immune checkpoints in vivo and can be targeted to enhance therapeutic antitumor immunity(2021)164 cited

→ Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly(2013)164 cited

→ Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling(2001)109 cited