Tianze Wu
Fudan University(CN)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Nanoplatforms for cancer theranostics, Cancer Mechanisms and Therapy, Synthesis and biological activity, Acute Myeloid Leukemia Research
Most-Cited Works
- → Design and synthesis of NQO1 responsive fluorescence probe and its application in bio-imaging for cancer diagnosis(2019)44 cited
- → Bioisosteric replacements of the indole moiety for the development of a potent and selective PI3Kδ inhibitor: Design, synthesis and biological evaluation(2021)21 cited
- → Hybrid nanoparticle–mediated simultaneous ROS scavenging and STING activation improve the antitumor immunity of in situ vaccines(2024)20 cited
- → Discovery of cinnoline derivatives as potent PI3K inhibitors with antiproliferative activity(2021)19 cited
- → Hollow carbon nanospheres dotted with Gd–Fe nanoparticles for magnetic resonance and photoacoustic imaging(2021)19 cited
- → Discovery of N-(2-chloro-5-(3-(pyridin-4-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yl)-4-fluorobenzenesulfonamide (FD274) as a highly potent PI3K/mTOR dual inhibitor for the treatment of acute myeloid leukemia(2023)7 cited
- → Discovery of a high potent PIM kinase inhibitor for acute myeloid leukemia based on N-pyridinyl amide scaffold by optimizing the fragments toward to Lys67 and Asp128/Glu171(2023)6 cited
- → A pyridinesulfonamide derivative FD268 suppresses cell proliferation and induces apoptosis via inhibiting PI3K pathway in acute myeloid leukemia(2022)4 cited
- → Systematical Evaluation of the Structure-Cardiotoxicity Relationship of 7-Azaindazole-based PI3K Inhibitors Designed by Bioisosteric Approach(2023)4 cited
- → A 40-nm CMOS 90-GHz Power Amplifier(2019)1 cited