John G. Houston
University of Dundee(GB)NHS Tayside(GB)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Computational Drug Discovery Methods, Innovative Microfluidic and Catalytic Techniques Innovation, Cholinesterase and Neurodegenerative Diseases, Acute Ischemic Stroke Management
Most-Cited Works
- → Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor(2010)184 cited
- → ??-Secretase Inhibitors for Alzheimer??s Disease(2006)128 cited
- → Discovery of (5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate (BMS-927711): An Oral Calcitonin Gene-Related Peptide (CGRP) Antagonist in Clinical Trials for Treating Migraine(2012)86 cited
- → The chemical-biological interface: developments in automated and miniaturised screening technology(1997)83 cited
- → Synthesis and biological evaluation of a library containing potentially 1600 amides / esters. A strategy for rapid compound generation and screening.(1994)69 cited
- → Pharmacodynamics of Selective Inhibition of γ-Secretase by Avagacestat(2012)63 cited
- → Chitin biosynthesis in Candida albicans grown in vitro and in vivo and its inhibition by nikkomycin Z(1992)57 cited
- → Case study: impact of technology investment on lead discovery at Bristol–Myers Squibb, 1998–2006(2008)48 cited
- → Application of Lean Manufacturing Concepts to Drug Discovery: Rapid Analogue Library Synthesis(2006)36 cited
- → Best Practices in Compound Management for Preserving Compound Integrity and Accurately Providing Samples for Assays(2009)32 cited