Javier de Vicente
Tetra Therapeutics (United States)(US)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, Hepatitis C virus research, RNA and protein synthesis mechanisms, Cytokine Signaling Pathways and Interactions, Quinazolinone synthesis and applications
Most-Cited Works
- → Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease(2022)237 cited
- → Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B(2013)37 cited
- → Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria(2020)36 cited
- → Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure–activity relationships of benzothiazine-substituted quinolinediones(2009)35 cited
- → Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: Structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides(2009)35 cited
- → Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity(2018)33 cited
- → Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors(2013)32 cited
- → Discovery of N-[4-[6-tert-Butyl-5-methoxy-8-(6-methoxy-2-oxo-1H-pyridin-3-yl)-3-quinolyl]phenyl]methanesulfonamide (RG7109), a Potent Inhibitor of the Hepatitis C Virus NS5B Polymerase(2013)31 cited
- → Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria(2018)29 cited
- → Structural and Biological Basis of Small Molecule Inhibition of Escherichia coli LpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis(2019)24 cited