Sam Lee
Johns Hopkins University(US)Johns Hopkins Medicine(US)
Publications by Year
Research Areas
Advanced biosensing and bioanalysis techniques, DNA and Nucleic Acid Chemistry, Pluripotent Stem Cells Research, RNA Interference and Gene Delivery, Analytical Chemistry and Chromatography
Most-Cited Works
- → Pharmacology of a Central Nervous System Delivered 2′-O-Methoxyethyl–Modified Survival of Motor Neuron Splicing Oligonucleotide in Mice and Nonhuman Primates(2014)269 cited
- → Short Antisense Oligonucleotides with Novel 2′−4′ Conformationaly Restricted Nucleoside Analogues Show Improved Potency without Increased Toxicity in Animals(2008)264 cited
- → Effects of Tenofovir Disoproxil Fumarate in Hepatitis B e Antigen-Positive Patients With Normal Levels of Alanine Aminotransferase and High Levels of Hepatitis B Virus DNA(2014)172 cited
- → Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages(2014)127 cited
- → Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver(2010)117 cited
- → Antisense Oligonucleotides Containing Conformationally Constrained 2′,4′-(N-Methoxy)aminomethylene and 2′,4′-Aminooxymethylene and 2′-O,4′-C-Aminomethylene Bridged Nucleoside Analogues Show Improved Potency in Animal Models(2010)72 cited
- → Synthesis, Improved Antisense Activity and Structural Rationale for the Divergent RNA Affinities of 3′-Fluoro Hexitol Nucleic Acid (FHNA and Ara-FHNA) Modified Oligonucleotides(2011)71 cited
- → Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolism(2023)61 cited
- → Amphoteric liposomes enable systemic antigen‐presenting cell–directed delivery of CD40 antisense and are therapeutically effective in experimental arthritis(2009)46 cited
- → Synthesis of Symmetric Fluorescently Labeled Poly(ethylene glycols) Using Phosphoramidites of Pyrenebutanol and Their Characterization by MALDI Mass Spectrometry(1996)40 cited