Hua Guan
Beijing Radiation Center(CN)
Publications by Year
Research Areas
DNA Repair Mechanisms, PARP inhibition in cancer therapy, CRISPR and Genetic Engineering, Ubiquitin and proteasome pathways, Mitochondrial Function and Pathology
Most-Cited Works
- → γH2AX foci formation in the absence of DNA damage: Mitotic H2AX phosphorylation is mediated by the DNA‐PKcs/CHK2 pathway(2013)134 cited
- → Exosome-packaged miR-1246 contributes to bystander DNA damage by targeting LIG4(2018)106 cited
- → Double‐strand DNA break repair: molecular mechanisms and therapeutic targets(2023)65 cited
- → RBX1 prompts degradation of EXO1 to limit the homologous recombination pathway of DNA double-strand break repair in G1 phase(2019)55 cited
- → TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1(2015)42 cited
- → The involvement of c-Myc in the DNA double-strand break repair via regulating radiation-induced phosphorylation of ATM and DNA-PKcs activity(2015)42 cited
- → PARP1 modulates METTL3 promoter chromatin accessibility and associated LPAR5 RNA m6A methylation to control cancer cell radiosensitivity(2023)40 cited
- → Quantitative proteomics reveals mitochondrial respiratory chain as a dominant target for carbon ion radiation: Delayed reactive oxygen species generation caused DNA damage(2018)38 cited
- → HUWE1-dependent DNA-PKcs neddylation modulates its autophosphorylation in DNA damage response(2020)36 cited
- → Dual Tumor-Targeting Nanocarrier System for siRNA Delivery Based on pRNA and Modified Chitosan(2017)31 cited