Alec J. Walker
Broad Institute(US)Boston Children's Hospital(US)Harvard University(US)Boston Children's Museum(US)
Publications by Year
Research Areas
CAR-T cell therapy research, Neuroinflammation and Neurodegeneration Mechanisms, Neuroblastoma Research and Treatments, Immunotherapy and Immune Responses, Immune Cell Function and Interaction
Most-Cited Works
- → Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes(2018)2,264 cited
- → 4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors(2015)1,752 cited
- → CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development(2018)453 cited
- → Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain(2022)420 cited
- → Tumor Antigen and Receptor Densities Regulate Efficacy of a Chimeric Antigen Receptor Targeting Anaplastic Lymphoma Kinase(2017)374 cited
- → Reduction of MDSCs with All-trans Retinoic Acid Improves CAR Therapy Efficacy for Sarcomas(2016)318 cited