James E. Bradner
Boston Biomedical (United States)(US)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Histone Deacetylase Inhibitors Research, Epigenetics and DNA Methylation, Cancer-related gene regulation, Multiple Myeloma Research and Treatments
Most-Cited Works
- → Selective inhibition of BET bromodomains(2010)4,233 cited
- → Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90(2005)749 cited
- → Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma(2012)596 cited
- → BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression(2016)425 cited
- → BET Bromodomains Mediate Transcriptional Pause Release in Heart Failure(2013)404 cited
- → Combined autophagy and proteasome inhibition(2014)372 cited
- → Models of human core transcriptional regulatory circuitries(2016)307 cited
- → Acetylation site specificities of lysine deacetylase inhibitors in human cells(2015)275 cited
- → Histone Deacetylase 6 and Heat Shock Protein 90 Control the Functions of Foxp3 + T-Regulatory Cells(2011)250 cited
- → Differentiation of NUT Midline Carcinoma by Epigenomic Reprogramming(2011)219 cited