John Cole
Franklin & Marshall College(US)University of Glasgow(GB)
Publications by Year
Research Areas
Epigenetics and DNA Methylation, Inflammatory Bowel Disease, Genetics, Aging, and Longevity in Model Organisms, Protein Degradation and Inhibitors, Acute Myeloid Leukemia Research
Most-Cited Works
- → Mitochondria are required for pro‐ageing features of the senescent phenotype(2016)753 cited
- → Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions(2017)197 cited
- → HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia(2014)162 cited
- → Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability(2016)102 cited
- → Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest(2015)92 cited
- → BRD4-mediated repression of p53 is a target for combination therapy in AML(2021)76 cited
- → Histone chaperone HIRA deposits histone H3.3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity(2017)68 cited
- → DNMT inhibitors reverse a specific signature of aberrant promoter DNA methylation and associated gene silencing in AML(2014)66 cited
- → Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function(2017)47 cited
- → Polarizing receptor activation dissociates fibroblast growth factor 2 mediated inhibition of myelination from its neuroprotective potential(2019)22 cited