Philip W. Howard
Spirogen (United Kingdom)(GB)
Publications by Year
Research Areas
HER2/EGFR in Cancer Research, Monoclonal and Polyclonal Antibodies Research, Cancer therapeutics and mechanisms, Cancer Treatment and Pharmacology, Synthesis and pharmacology of benzodiazepine derivatives
Most-Cited Works
- → A Potent Anti-CD70 Antibody–Drug Conjugate Combining a Dimeric Pyrrolobenzodiazepine Drug with Site-Specific Conjugation Technology(2013)243 cited
- → Antibody–drug conjugates – a perfect synergy(2012)119 cited
- → Discovery of Peptidomimetic Antibody–Drug Conjugate Linkers with Enhanced Protease Specificity(2017)104 cited
- → Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody–Drug Conjugate Targeting PSMA, in Preclinical Models of Prostate Cancer(2018)47 cited
- → Integrin αvβ6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus(2020)46 cited
- → Preclinical Evaluation of MEDI0641, a Pyrrolobenzodiazepine-Conjugated Antibody–Drug Conjugate Targeting 5T4(2017)45 cited
- → Pyrrolobenzodiazepine Antibody-Drug Conjugates Designed for Stable Thiol Conjugation(2017)25 cited
- → A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis(2019)21 cited
- → Optimization of the Antitumor Activity of Sequence-specific Pyrrolobenzodiazepine Derivatives Based on their Affinity for ABC Transporters(2010)16 cited
- → An Alternative Focus for Route Design for the Synthesis of Antibody–Drug Conjugate Payloads(2019)13 cited