Lori S. Friedman
Sunesis (United States)(US)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Advanced Breast Cancer Therapies, Estrogen and related hormone effects, FOXO transcription factor regulation, Chronic Lymphocytic Leukemia Research
Most-Cited Works
- → RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth(2010)1,616 cited
- → Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941(2009)825 cited
- → Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome(2004)770 cited
- → The Identification of 2-(1H-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer(2008)741 cited
- → Involvement of Brca2 in DNA Repair(1998)630 cited
- → Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families(1994)625 cited