Laura A. Nguyen
AVEO Oncology (United States)(US)Sanofi (United States)(US)
Publications by Year
Research Areas
HIV Research and Treatment, HIV/AIDS drug development and treatment, Cytomegalovirus and herpesvirus research, Immune Cell Function and Interaction, interferon and immune responses
Most-Cited Works
- → The Retroviral Restriction Ability of SAMHD1, but Not Its Deoxynucleotide Triphosphohydrolase Activity, Is Regulated by Phosphorylation(2013)307 cited
- → Tight Interplay among SAMHD1 Protein Level, Cellular dNTP Levels, and HIV-1 Proviral DNA Synthesis Kinetics in Human Primary Monocyte-derived Macrophages(2012)202 cited
- → Mouse SAMHD1 Has Antiretroviral Activity and Suppresses a Spontaneous Cell-Intrinsic Antiviral Response(2013)158 cited
- → Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1(2012)140 cited
- → Role of CD44s and CD44v6 on human breast cancer cell adhesion, migration, and invasion(2009)111 cited
- → Ribonucleoside Triphosphates as Substrate of Human Immunodeficiency Virus Type 1 Reverse Transcriptase in Human Macrophages(2010)102 cited
- → A bivalent Epstein-Barr virus vaccine induces neutralizing antibodies that block infection and confer immunity in humanized mice(2022)93 cited
- → Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d]pyrimidine non-nucleoside inhibitors(2018)76 cited
- → Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect(2016)59 cited
- → Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells(2017)56 cited