Masami Ohtsuka
Daiichi-Sankyo (Japan)(JP)
Publications by Year
Research Areas
Carbohydrate Chemistry and Synthesis, Antibiotic Resistance in Bacteria, Synthetic Organic Chemistry Methods, Microbial Natural Products and Biosynthesis, Traditional and Medicinal Uses of Annonaceae
Most-Cited Works
- → MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 7: Highly soluble and in vivo active quaternary ammonium analogue D13-9001, a potential preclinical candidate(2007)130 cited
- → Total synthesis of antibiotic hygromycin A(1991)90 cited
- → Total synthesis of (+)-lycoricidine and its 2-epimer from D-glucose(1993)88 cited
- → MexAB-OprM-Specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: Discovery and early strategies for lead optimization(2003)82 cited
- → Stereoselective total synthesis of (+)-lycoricidine(1991)77 cited
- → Synthesis of Optically Active Substituted Cyclohexenones from Carbohydrates by Catalytic Ferrier Rearrangement(1991)71 cited
- → MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 3: Optimization of potency in the pyridopyrimidine series through the application of a pharmacophore model(2003)65 cited
- → MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 6: Exploration of aromatic substituents(2006)59 cited
- → MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 2: achieving activity in vivo through the use of alternative scaffolds(2003)58 cited
- → Total Synthesis of (+)-7-Deoxypancratistatin and (+)-7-Deoxy-trans-dihydronarciclasine(1996)51 cited