James C. Sacchettini
Texas A&M University(US)
Publications by Year
Research Areas
Tuberculosis Research and Epidemiology, Mycobacterium research and diagnosis, Antibiotic Resistance in Bacteria, Pneumocystis jirovecii pneumonia detection and treatment, Biochemical and Molecular Research
Most-Cited Works
- → Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase(2000)1,349 cited
- → Modification of the NADH of the Isoniazid Target (InhA) from Mycobacterium tuberculosis(1998)676 cited
- → Crystal Structure and Function of the Isoniazid Target of Mycobacterium tuberculosis(1995)429 cited
- → Enzymic Characterization of the Target for Isoniazid in Mycobacterium tuberculosis(1995)368 cited
- → Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid(2006)323 cited
- → Mechanism of thioamide drug action against tuberculosis and leprosy(2007)293 cited
- → Crystal Structure of the Mycobacterium tuberculosis Enoyl-ACP Reductase, InhA, in Complex with NAD+ and a C16 Fatty Acyl Substrate(1999)288 cited
- → Altered NADH/NAD + Ratio Mediates Coresistance to Isoniazid and Ethionamide in Mycobacteria(2005)281 cited
- → Inactivation of the inhA -Encoded Fatty Acid Synthase II (FASII) Enoyl-Acyl Carrier Protein Reductase Induces Accumulation of the FASI End Products and Cell Lysis of Mycobacterium smegmatis(2000)278 cited
- → Targeting Tuberculosis and Malaria through Inhibition of Enoyl Reductase(2003)261 cited