Denice M. Spero
Boehringer Ingelheim (United States)(US)
Publications by Year
Research Areas
Asymmetric Synthesis and Catalysis, Chemical Synthesis and Analysis, Cyclopropane Reaction Mechanisms, Catalytic C–H Functionalization Methods, Protease and Inhibitor Mechanisms
Most-Cited Works
- → Total synthesis of halichondrin B and norhalichondrin B(1992)389 cited
- → Rhodium (II) catalyzed reactions of diazo-carbonyl compounds(1991)302 cited
- → Design and Synthesis of Dipeptide Nitriles as Reversible and Potent Cathepsin S Inhibitors(2002)83 cited
- → Discovery of potent and selective PKC-θ inhibitors(2006)69 cited
- → Regiospecific control of Rh(II) carbenoids in the C-H insertion reaction(1992)63 cited
- → Aryl radical-initiated cyclizations: Effect of aryl substituents on ring-size(1986)53 cited
- → A Novel Method for the Asymmetric Synthesis of α,α-Disubstituted Alkylamines via Grignard Additions to Ketimines(1997)48 cited
- → Highly Diastereoselective Addition of Grignard Reagents to Aliphatic, Enolizable N-Alkylketimines and 2,2-Disubstituted 1,3-Oxazolidines. Asymmetric Synthesis of the Antidepressant Cericlamine(1999)37 cited
- → Evaluation of some preparations of trialkoxyphthalic acid derivatives(1987)37 cited
- → Benzoxazolamines and Benzothiazolamines: Potent, Enantioselective Inhibitors of Leukotriene Biosynthesis with a Novel Mechanism of Action(1994)34 cited