Randall K. Johnson
Mississippi College(US)
Publications by Year
Research Areas
Cancer therapeutics and mechanisms, Marine Sponges and Natural Products, Metal complexes synthesis and properties, Microbial Natural Products and Biosynthesis, Bioactive Compounds and Antitumor Agents
Most-Cited Works
- → Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity(1991)516 cited
- Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells.(1991)
- Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia.(1979)
- → Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway(1999)423 cited
- → Modification of the hydroxylactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity(1989)411 cited
- Evaluation of the in vivo antitumor activity and in vitro cytotoxic properties of auranofin, a coordinated gold compound, in murine tumor models.(1985)
- → Dominant Missense Mutations in a Novel Yeast Protein related to Mammalian Phosphatidylinositol 3-Kinase and VPS34 Abrogate Rapamycin Cytotoxicity(1993)276 cited