Shailen K. Joshi
AbbVie (United States)(US)
Publications by Year
Research Areas
Pain Mechanisms and Treatments, Ion Channels and Receptors, Ion channel regulation and function, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography
Most-Cited Works
- → A-803467, a potent and selective Na v 1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat(2007)520 cited
- → Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation(2011)269 cited
- → Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia(2009)145 cited
- → Estimating Efficacy and Drug ED50's Using von Frey Thresholds: Impact of Weber's Law and Log Transformation(2012)131 cited
- → Discovery and Biological Evaluation of 5-Aryl-2-furfuramides, Potent and Selective Blockers of the Nav1.8 Sodium Channel with Efficacy in Models of Neuropathic and Inflammatory Pain(2008)84 cited
- → Pharmacology of Modality-Specific Transient Receptor Potential Vanilloid-1 Antagonists That Do Not Alter Body Temperature(2012)83 cited
- → A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats(2014)72 cited
- → A-995662 [(R)-8-(4-methyl-5-(4-(trifluoromethyl)phenyl)oxazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol], a novel, selective TRPV1 receptor antagonist, reduces spinal release of glutamate and CGRP in a rat knee joint pain model(2010)64 cited
- → A-887826 is a structurally novel, potent and voltage-dependent Nav1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats(2010)56 cited
- → Contributions of Central and Peripheral TRPV1 Receptors to Mechanically Evoked and Spontaneous Firing of Spinal Neurons in Inflamed Rats(2008)56 cited