Maaike van den Born
Hubrecht Institute for Developmental Biology and Stem Cell Research(NL)
Publications by Year
Research Areas
Wnt/β-catenin signaling in development and cancer, Cancer Cells and Metastasis, Digestive system and related health, Epigenetics and DNA Methylation, Cancer-related gene regulation
Most-Cited Works
- → Identification of stem cells in small intestine and colon by marker gene Lgr5(2007)5,629 cited
- → Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts(2010)2,447 cited
- → Crypt stem cells as the cells-of-origin of intestinal cancer(2008)2,142 cited
- → The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells(2002)2,000 cited
- → Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells(2010)1,952 cited
- → Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro(2010)1,530 cited
- → Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells(2005)1,510 cited
- → Lineage Tracing Reveals Lgr5 + Stem Cell Activity in Mouse Intestinal Adenomas(2012)1,057 cited
- → Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids(2018)820 cited
- → Dll1+ secretory progenitor cells revert to stem cells upon crypt damage(2012)777 cited