Stacey L. Becker
Pfizer (United States)(US)
Publications by Year
Research Areas
Drug Transport and Resistance Mechanisms, Alzheimer's disease research and treatments, Computational Drug Discovery Methods, Cholinesterase and Neurodegenerative Diseases, Chemical Synthesis and Analysis
Most-Cited Works
- → THE IMPACT OF P-GLYCOPROTEIN ON THE DISPOSITION OF DRUGS TARGETED FOR INDICATIONS OF THE CENTRAL NERVOUS SYSTEM: EVALUATION USING THE MDR1A/1B KNOCKOUT MOUSE MODEL(2004)440 cited
- → Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor(2012)420 cited
- → Use of a Physiologically Based Pharmacokinetic Model to Study the Time to Reach Brain Equilibrium: An Experimental Analysis of the Role of Blood-Brain Barrier Permeability, Plasma Protein Binding, and Brain Tissue Binding(2005)182 cited
- → Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration(2006)160 cited
- → Discovery, SAR, and Pharmacokinetics of a Novel 3-Hydroxyquinolin-2(1H)-one Series of Potentd-Amino Acid Oxidase (DAAO) Inhibitors(2009)109 cited
- → Metabolism-Directed Design of Oxetane-Containing Arylsulfonamide Derivatives as γ-Secretase Inhibitors(2011)105 cited
- → EVALUATION OF THE UTILITY OF BRAIN SLICE METHODS TO STUDY BRAIN PENETRATION(2006)78 cited
- → Application of Structure-Based Drug Design and Parallel Chemistry to Identify Selective, Brain Penetrant, In Vivo Active Phosphodiesterase 9A Inhibitors(2012)55 cited
- → Pharmacodynamics and Pharmacokinetics of the γ-Secretase Inhibitor PF-3084014(2010)50 cited
- → Modulation of NMDA receptor function by inhibition of d-amino acid oxidase in rodent brain(2011)40 cited