Erick A. Goldman
Exelixis (United States)(US)
Publications by Year
Research Areas
Blood Coagulation and Thrombosis Mechanisms, Chemical Synthesis and Analysis, Synthesis and Catalytic Reactions, Peptidase Inhibition and Analysis, Protease and Inhibitor Mechanisms
Most-Cited Works
- → Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor(2009)105 cited
- → Antimalarial Activities of Novel SyntheticCysteine ProteaseInhibitors(2003)78 cited
- → Design, Synthesis, and Evolution of a Novel, Selective, and Orally Bioavailable Class of Thrombin Inhibitors: P1-Argininal Derivatives Incorporating P3-P4 Lactam Sulfonamide Moieties(1996)64 cited
- → Inhibitory effect of carboxylic acid group on hERG binding(2006)51 cited
- → Design and synthesis of a novel class of thrombin inhibitors incorporating heterocyclic dipeptide surrogates(1997)32 cited
- → Novel benzo-fused lactam scaffolds as factor Xa inhibitors(1999)29 cited
- → Synthesis and biological activity of peptidyl aldehyde urokinase inhibitors(2000)26 cited
- → Rational design, synthesis, and serine protease inhibitory activity of a novel P1-argininal derivative featuring a conformationally constrained P2–P3 bicyclic lactam moiety(1997)26 cited
- → 1-(2-Naphthyl)-1 H -pyrazole-5-carboxylamides as potent factor Xa inhibitors. Part 2: A survey of P4 motifs(2004)25 cited
- → Design, synthesis, and SAR of anthranilamide-based factor Xa inhibitors incorporating substituted biphenyl P4 motifs(2004)25 cited