a public good project by the
Synthesis
Company
of California

© 2026

Saeho Chong | doi.page

0 works0 citations0 h-index

Saeho Chong

Alnylam Pharmaceuticals (United States)(US)

Publications by Year

Research Areas

Drug Transport and Resistance Mechanisms, RNA Interference and Gene Delivery, Pharmacogenetics and Drug Metabolism, Pharmacological Effects and Toxicity Studies, Advanced biosensing and bioanalysis techniques

Most-Cited Works

→ A novel vesicular carrier, transethosome, for enhanced skin delivery of voriconazole: Characterization and in vitro/in vivo evaluation(2011)365 cited
→ Current methodologies used for evaluation of intestinal permeability and absorption(2000)312 cited
→ Cell culture-based models for intestinal permeability: A critique(2005)274 cited
→ Current industrial practices of assessing permeability and P-glycoprotein interaction(2006)258 cited
→ Commonly used surfactant, Tween 80, improves absorption of P-glycoprotein substrate, digoxin, in rats(2003)244 cited
→ Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates(2022)228 cited
→

Discovery of (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity

(2000)

134 cited

→ Chitosan oligosaccharide–arachidic acid-based nanoparticles for anti-cancer drug delivery(2012)113 cited

→ In Vitro Permeability Through Caco-2 Cells is not Quantitatively Predictive of in Vivo Absorption for Peptide-Like Drugs Absorbed via the Dipeptide Transporter System(1996)111 cited

→ Prediction of the Oral Absorption of Low-Permeability Drugs Using Small Intestine-Like 2/4/A1 Cell Monolayers(2003)109 cited