Lai N. Chan
Case Western Reserve University(US)
Publications by Year
Research Areas
Acute Lymphoblastic Leukemia research, Chronic Myeloid Leukemia Treatments, Chronic Lymphocytic Leukemia Research, CAR-T cell therapy research, Ubiquitin and proteasome pathways
Most-Cited Works
- → R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis(2021)336 cited
- → A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA.(1989)248 cited
- → Metabolic gatekeeper function of B-lymphoid transcription factors(2017)239 cited
- → The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth(2009)143 cited
- → Self-Enforcing Feedback Activation between BCL6 and Pre-B Cell Receptor Signaling Defines a Distinct Subtype of Acute Lymphoblastic Leukemia(2015)138 cited
- → Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia(2015)133 cited
- → B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies(2018)131 cited
- → PTEN opposes negative selection and enables oncogenic transformation of pre-B cells(2016)119 cited
- → IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells(2020)102 cited
- → Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia(2014)97 cited