Penelope Roques
Southampton General Hospital(GB)St Mary's Hospital(GB)National Hospital for Neurology and Neurosurgery(GB)University College London(GB)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Bioinformatics and Genomic Networks, Amyloidosis: Diagnosis, Treatment, Outcomes, Dementia and Cognitive Impairment Research, Computational Drug Discovery Methods
Most-Cited Works
- → Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease(1991)4,633 cited
- → Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene(1991)1,212 cited
- → Apolipoprotein E, ɛ4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region(1994)434 cited
- → A mutation in Alzheimerʼs disease destroying a splice acceptor site in the presenilin-1 gene(1995)256 cited
- → Deficits in cerebral glucose metabolism demonstrated by positron emission tomography in individuals at risk of familial Alzheimer's disease(1995)250 cited
- → Screening for mutations in the open reading frame and promoter of the β-amyloid precursor protein gene in familial Alzheimer's disease: identification of a further family with APP717 Val→lle(1992)