David Westaway
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Computational Drug Discovery Methods, Cellular transport and secretion, Cholinesterase and Neurodegenerative Diseases, Trace Elements in Health
Most-Cited Works
- → Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease(2000)1,428 cited
- → Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model(2006)361 cited
- → Presenilin 1 Controls γ-Secretase Processing of Amyloid Precursor Protein in Pre-Golgi Compartments of Hippocampal Neurons(1999)312 cited
- → TMP21 is a presenilin complex component that modulates γ-secretase but not ɛ-secretase activity(2006)296 cited
- → Examining the zinc binding site of the amyloid‐β peptide(2000)113 cited
- → Presenilin 1 Mutations Activate γ42-Secretase but Reciprocally Inhibit ε-Secretase Cleavage of Amyloid Precursor Protein (APP) and S3-Cleavage of Notch(2002)107 cited
- → Transgenic mouse models of Alzheimer’s disease(2000)101 cited
- → Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes(2000)87 cited
- → Dissociated phenotypes in presenilin transgenic mice define functionally distinct γ-secretases(2005)84 cited
- → The Presenilin Proteins Are Components of Multiple Membrane-bound Complexes That Have Different Biological Activities(2004)75 cited