Mehran F. Moghaddam
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Pharmacogenetics and Drug Metabolism, Metabolomics and Mass Spectrometry Studies, Seaweed-derived Bioactive Compounds, Melanoma and MAPK Pathways
Most-Cited Works
- → Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase(1997)306 cited
- → Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma(2020)209 cited
- → Efficiency in Drug Discovery: Liver S9 Fraction Assay As a Screen for Metabolic Stability(2016)135 cited
- → Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor(2011)114 cited
- → Oxylipin metabolism in the red alga Gracilariopsis lemaneiformis: Mechanism of formation of vicinal dihydroxy fatty acids(1991)100 cited
- → Pomalidomide Shows Significant Therapeutic Activity against CNS Lymphoma with a Major Impact on the Tumor Microenvironment in Murine Models(2013)96 cited
- → Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115(2015)72 cited
- → Novel cytotoxic peptides from the tropical marine cyanobacteriumHormothamnion enteromorphoides 1. Discovery, isolation and initial chemical and biological characterization of the hormothamnins from wild and cultured material(1989)70 cited
- → The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen(2017)59 cited
- → Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity(2012)57 cited