Simon F. Semus
GlaxoSmithKline (United States)(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Protein Kinase Regulation and GTPase Signaling, Protein Structure and Dynamics, Cannabis and Cannabinoid Research, Ion channel regulation and function
Most-Cited Works
- → A Critical Assessment of Docking Programs and Scoring Functions(2005)1,688 cited
- → HINT: A new method of empirical hydrophobic field calculation for CoMFA(1991)334 cited
- → Development of Dihydropyridone Indazole Amides as Selective Rho-Kinase Inhibitors(2006)154 cited
- → The Role of Transmembrane Helix 5 in Agonist Binding to the Human H3 Receptor(2002)80 cited
- → Potent, Selective and Orally Bioavailable Dihydropyrimidine Inhibitors of Rho Kinase (ROCK1) as Potential Therapeutic Agents for Cardiovascular Diseases(2008)72 cited
- → Discovery of Aminofurazan-azabenzimidazoles as Inhibitors of Rho-Kinase with High Kinase Selectivity and Antihypertensive Activity(2006)71 cited
- → Modeling the Cannabinoid Receptor: A Three-Dimensional Quantitative Structure-Activity Analysis(1991)59 cited
- → NMR Structure of Free RGS4 Reveals an Induced Conformational Change upon Binding Gα(2000)38 cited
- → Pharmacological evaluation of iodo and nitro analogs of Δ8-THC and Δ9-THC(1993)35 cited
- → 2-[2-(3,4-Dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic Acid (PD-307243) Causes Instantaneous Current through Human Ether-a-go-go-Related Gene Potassium Channels(2007)34 cited