Tak W. Mak
Ontario Institute for Cancer Research(CA)University of Toronto(CA)
Publications by Year
Research Areas
T-cell and B-cell Immunology, Immune Cell Function and Interaction, Immunotherapy and Immune Responses, CAR-T cell therapy research, Immunodeficiency and Autoimmune Disorders
Most-Cited Works
- → Tumor necrosis factor-α is required in the protective immune response against mycobacterium tuberculosis in mice(1995)1,683 cited
- → ICOS is essential for effective T-helper-cell responses(2001)666 cited
- → A point mutation in CD28 distinguishes proliferative signals from survival signals(2001)202 cited
- → Role of ICOS versus CD28 in antiviral immunity(2002)88 cited
- → Knockout mice: a paradigm shift in modern immunology(2001)78 cited
- → CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny(1993)69 cited
- → T lymphocyte development in p56lck deficient mice: allelic exclusion of the TcR β locus is incomplete but thymocyte development is not restored by TcR β or TcR αβ transgenes(1995)52 cited
- → Genetically modified animals and immunodeficiency(1993)24 cited
- → Gaining Insights into the Ontogeny and Activation of T Cells Through the Use of Gene-Targeted Mutant Mice(1996)4 cited