Thomas J. Sowin
Abbott (United States)(US)
Publications by Year
Research Areas
DNA Repair Mechanisms, Cancer-related Molecular Pathways, Chemical Synthesis and Analysis, Cancer therapeutics and mechanisms, Microtubule and mitosis dynamics
Most-Cited Works
- → Chk1 Mediates S and G2 Arrests through Cdc25A Degradation in Response to DNA-damaging Agents(2003)379 cited
- → Design, Synthesis, and Structural Analysis of Influenza Neuraminidase Inhibitors Containing Pyrrolidine Cores(2001)132 cited
- → Selective Chk1 inhibitors differentially sensitize p53‐deficient cancer cells to cancer therapeutics(2006)129 cited
- → Influenza Neuraminidase Inhibitors: Structure-Based Design of a Novel Inhibitor Series(2003)128 cited
- → Synthesis of α-amino and α-alkoxy aldehydes via oxoammonium oxidation(1992)121 cited
- → Differential roles of checkpoint kinase 1, checkpoint kinase 2, and mitogen-activated protein kinase–activated protein kinase 2 in mediating DNA damage–induced cell cycle arrest: implications for cancer therapy(2006)94 cited
- Human Chk1 expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.(2003)
- → Stereocontrolled synthesis of C2-symmetric and pseudo-C2-symmetric diamino alcohols and diols for use in HIV protease inhibitors(1992)91 cited
- → Structure-Based Design, Synthesis, and Biological Evaluation of Potent and Selective Macrocyclic Checkpoint Kinase 1 Inhibitors(2007)88 cited
- → A novel mechanism of checkpoint abrogation conferred by Chk1 downregulation(2004)88 cited