Bradford Graves
Forma Therapeutics (United States)(US)La Roche College(US)
Publications by Year
Research Areas
Cancer-related Molecular Pathways, Chemical Synthesis and Analysis, Ubiquitin and proteasome pathways, Protein Degradation and Inhibitors, Click Chemistry and Applications
Most-Cited Works
- → In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2(2004)4,638 cited
- → Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy(2013)653 cited
- → Discovery of RG7388, a Potent and Selective p53–MDM2 Inhibitor in Clinical Development(2013)586 cited
- → Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study(2012)555 cited
- → Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains(1994)397 cited
- → Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development(2013)373 cited