Zhijun Kang
The University of Texas MD Anderson Cancer Center(US)
Publications by Year
Research Areas
Cancer, Hypoxia, and Metabolism, Mitochondrial Function and Pathology, RNA modifications and cancer, ATP Synthase and ATPases Research, Phosphodiesterase function and regulation
Most-Cited Works
- → An inhibitor of oxidative phosphorylation exploits cancer vulnerability(2018)924 cited
- → Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib(2020)102 cited
- → Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease(2004)99 cited
- → An enolase inhibitor for the targeted treatment of ENO1-deleted cancers(2020)98 cited
- → Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties(2020)89 cited
- → Application of Structure-Based Drug Design and Parallel Chemistry to Identify Selective, Brain Penetrant, In Vivo Active Phosphodiesterase 9A Inhibitors(2012)55 cited
- → Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia(2011)52 cited
- → Potent and cellularly active 4-aminoimidazole inhibitors of cyclin-dependent kinase 5/p25 for the treatment of Alzheimer’s disease(2009)47 cited
- → Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer(2021)42 cited
- → Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor(2017)32 cited