Lain‐Yen Hu

Publications by Year

Research Areas

Ion channel regulation and function, Chemical Synthesis and Analysis, Neuroscience and Neuropharmacology Research, Nail Diseases and Treatments, Estrogen and related hormone effects

Most-Cited Works

• → Discovery, SAR, and Pharmacokinetics of a Novel 3-Hydroxyquinolin-2(1H)-one Series of Potentd-Amino Acid Oxidase (DAAO) Inhibitors(2009)109 cited
• → Role of specific aminotransferases in de novo glutamate synthesis and redox shuttling in the retina(2001)91 cited
• → Synthesis and Pharmacological Evaluation of N-(2,5-Disubstituted phenyl)-N‘-(3-substituted phenyl)-N‘-methylguanidines As N-Methyl-d-aspartate Receptor Ion-Channel Blockers(1997)83 cited
• → Comparison of artificial sebum with human and hamster sebum samples(2008)57 cited
• → Design, Synthesis, and Pharmacological Evaluation of Conformationally Constrained Analogues of N,N‘-Diaryl- and N-Aryl-N-aralkylguanidines as Potent Inhibitors of Neuronal Na+ Channels(1998)44 cited
• → Synthesis of a Series of 4-Benzyloxyaniline Analogues as Neuronal N-Type Calcium Channel Blockers with Improved Anticonvulsant and Analgesic Properties(1999)41 cited
• → Inhibition of cathepsin B and papain by peptidyl α-keto esters, α-keto amides, α-diketones, and α-keto acids(1990)33 cited
• → The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases(2005)32 cited
• → Neuroprotective Use‐Dependent Blockers of Na+ and Ca2+ Channels Controlling Presynaptic Release of Glutamatea(1995)29 cited
• → The discovery of [1-(4-dimethylamino-benzyl)-piperidin-4-yl]-[4-(3,3-dimethylbutyl)-phenyl]-(3-methyl-but-2-enyl)-amine, an N-type Ca+2 channel blocker with oral activity for analgesia(2000)29 cited