Yoshikazu Ohta
Publications by Year
Research Areas
Microtubule and mitosis dynamics, Cancer-related Molecular Pathways, HER2/EGFR in Cancer Research, Cancer, Hypoxia, and Metabolism, Monoclonal and Polyclonal Antibodies Research
Most-Cited Works
- → Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein(2011)417 cited
- → Design and Synthesis of Novel Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors Bearing a Pyrrolo[3,2-d]pyrimidine Scaffold(2011)211 cited
- → Structure-Based Approach for the Discovery of Pyrrolo[3,2-d]pyrimidine-Based EGFR T790M/L858R Mutant Inhibitors(2012)163 cited
- → Studies on Disease-Modifying Antirheumatic Drugs: Synthesis of Novel Quinoline and Quinazoline Derivatives and Their Anti-inflammatory Effect(1996)149 cited
- → Design and synthesis of novel pyrimido[4,5-b]azepine derivatives as HER2/EGFR dual inhibitors(2013)73 cited
- → Increased phosphorylation of Akt in triple‐negative breast cancers(2007)64 cited
- → Analysis of circulating tumor cells derived from advanced gastric cancer(2015)51 cited
- → Biological Characterization of TAK-901, an Investigational, Novel, Multitargeted Aurora B Kinase Inhibitor(2013)44 cited
- → Design and Synthesis of Pyrrolo[3,2-d]pyrimidine Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors: Exploration of Novel Back-Pocket Binders(2012)43 cited
- → Design and synthesis of pyrrolo[3,2-d]pyrimidine HER2/EGFR dual inhibitors: Improvement of the physicochemical and pharmacokinetic profiles for potent in vivo anti-tumor efficacy(2012)28 cited