Kenneth R. Korzekwa
Temple University(US)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Analytical Chemistry and Chromatography, Drug Transport and Resistance Mechanisms, Computational Drug Discovery Methods, Chemical Reactions and Isotopes
Most-Cited Works
- → Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions(1992)601 cited
- → Impaired (S)-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9(1994)492 cited
- → THE HUMAN CYP3A SUBFAMILY: PRACTICAL CONSIDERATIONS*(2000)211 cited
- → Role of human cytochrome P450 3A4 and 3A5 in the metabolism of taxotere and its derivatives: enzyme specificity, interindividual distribution and metabolic contribution in human liver(1998)190 cited
- → Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamil(1999)178 cited
- → The role of 12 cDNA‐expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans‐7, 8‐dihydrodiol(1994)166 cited
- → Human CYP2C9 and CYP2A6 Mediate Formation of the Hepatotoxin 4-Ene-Valproic Acid(1997)158 cited
- → Theoretical studies on cytochrome P-450 mediated hydroxylation: a predictive model for hydrogen atom abstractions(1990)138 cited
- → Estradiol Metabolism by Complementary Deoxyribonucleic Acid-Expressed Human Cytochrome P450s(1990)130 cited
- → Computational Models for Cytochrome P450: A Predictive Electronic Model for Aromatic Oxidation and Hydrogen Atom Abstraction(2002)121 cited