Jianxia Shi
Ideaya Biosciences (United States)(US)
Publications by Year
Research Areas
Phosphodiesterase function and regulation, Cholinesterase and Neurodegenerative Diseases, Receptor Mechanisms and Signaling, Cancer-related gene regulation, Protein Structure and Dynamics
Most-Cited Works
- → Allosteric Inhibition of the Protein-Protein Interaction between the Leukemia-Associated Proteins Runx1 and CBFβ(2007)117 cited
- → A fully automated plasma protein precipitation sample preparation method for LC–MS/MS bioanalysis(2007)73 cited
- → Energetic and Functional Contribution of Residues in the Core Binding Factor β (CBFβ) Subunit to Heterodimerization with CBFα(2000)63 cited
- → Biophysical characterization of interactions between the core binding factor α and β subunits and DNA(2000)49 cited
- → Protein Signal Assignments Using Specific Labeling and Cell-Free Synthesis(2004)46 cited
- → Design, Optimization, and Biological Evaluation of Novel Keto-Benzimidazoles as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A)(2013)43 cited
- → Discovery of Clinical Candidate 1-(4-(3-(4-(1H-Benzo[d]imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)ethanone (AMG 579), A Potent, Selective, and Efficacious Inhibitor of Phosphodiesterase 10A (PDE10A)(2014)36 cited
- → Rapid Identification of a Novel Small Molecule Phosphodiesterase 10A (PDE10A) Tracer(2012)28 cited
- → Discovery of Novel Imidazo[4,5-b]pyridines as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A)(2014)25 cited
- → Development of a robust and sensitive LC–MS/MS method for the determination of adenine in plasma of different species and its application to in vivo studies(2011)22 cited