Xin‐Jie Chu
Publications by Year
Research Areas
Synthetic Organic Chemistry Methods, Regulation of Appetite and Obesity, Biochemical Analysis and Sensing Techniques, Cancer-related Molecular Pathways, Chemical Synthesis and Analysis
Most-Cited Works
- → Discovery of RG7388, a Potent and Selective p53–MDM2 Inhibitor in Clinical Development(2013)586 cited
- → Total Synthesis of Vancomycin—Part 1: Design and Development of Methodology(1999)157 cited
- → Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), A Potent and Selective Cyclin-Dependent Kinase Inhibitor with Significant in Vivo Antitumor Activity(2006)116 cited
- → In vitro and in vivo activity of R547: a potent and selective cyclin-dependent kinase inhibitor currently in phase I clinical trials(2006)102 cited
- → Total Synthesis of Brevetoxin A: Part 1: First Generation Strategy and Construction of BCD Ring System(1999)90 cited
- → Discovery of Potent and Orally Active p53-MDM2 Inhibitors RO5353 and RO2468 for Potential Clinical Development(2013)86 cited
- → Discovery of potent and selective spiroindolinone MDM2 inhibitor, RO8994, for cancer therapy(2014)56 cited
- → Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections(2019)45 cited
- → Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors(2017)43 cited
- → Opportunities and Challenges of Developing Peptide Drugs in the Pharmaceutical Industry(2009)38 cited