Gaétan Ladouceur
Center for Drug Evaluation and Research(US)
Publications by Year
Research Areas
Diabetes Treatment and Management, Chemical Synthesis and Analysis, Receptor Mechanisms and Signaling, Synthetic Organic Chemistry Methods, Synthesis of Organic Compounds
Most-Cited Works
- → FDA Approval Summary: Olaparib Monotherapy in Patients with Deleterious Germline BRCA-Mutated Advanced Ovarian Cancer Treated with Three or More Lines of Chemotherapy(2015)515 cited
- → FDA Approval Summary: Lenvatinib for Progressive, Radio-iodine–Refractory Differentiated Thyroid Cancer(2015)77 cited
- → Discovery of 5-Hydroxyalkyl-4-phenylpyridines as a New Class of Glucagon Receptor Antagonists(2002)38 cited
- → Synthesis and evaluation of [125I]-(S)-iodozacopride, a high affinity radioligand for 5HT3 receptors(1993)28 cited
- → Synthetic studies targeted at the cytotoxic 8,9-seco-ent-kaurene diterpenes. Concise complementary stereocontrolled construction of the bridgehead olefin core(1989)26 cited
- → Optimization of the 4-aryl group of 4-aryl-pyridine glucagon antagonists: development of an efficient, alternative synthesis(2002)16 cited
- → Integration of optimized substituent patterns to produce highly potent 4-aryl-pyridine glucagon receptor antagonists(2002)13 cited
- → Application of the Anionic Oxy-Cope Rearrangement to Stereocontrolled Synthesis of the A/B Subunit of Cytoxic 8,9-Seco-ent-kaurenes(1992)12 cited
- → Structure elucidation by synthesis of four metabolites of the antitumor drug ENMD-1198 detected in human plasma samples(2009)11 cited
- → Synthesis of optically active 6-substituted 2-(aminomethyl)chromans(2004)8 cited