Kathy Boxall
Institute of Cancer Research(GB)Cancer Research UK(GB)
Publications by Year
Research Areas
Heat shock proteins research, Microtubule and mitosis dynamics, Enzyme Structure and Function, ATP Synthase and ATPases Research, Endoplasmic Reticulum Stress and Disease
Most-Cited Works
- → NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis(2008)476 cited
- → 4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer(2007)442 cited
- → Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms(2004)266 cited
- → Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues(2007)142 cited
- → In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors(2007)112 cited
- → The Preclinical Pharmacology and Therapeutic Activity of the Novel CHK1 Inhibitor SAR-020106(2010)101 cited
- → CCT244747 Is a Novel Potent and Selective CHK1 Inhibitor with Oral Efficacy Alone and in Combination with Genotoxic Anticancer Drugs(2012)92 cited
- → Structure-Based Design of Orally Bioavailable 1H-Pyrrolo[3,2-c]pyridine Inhibitors of Mitotic Kinase Monopolar Spindle 1 (MPS1)(2013)79 cited
- → Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: SAR and Structural Characterization(2010)70 cited
- → The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eμ-MYC driven B-cell lymphoma(2015)68 cited