Charles A. Omer
C3J Therapeutics (United States)(US)Trellis Bioscience (United States)(US)Helix Biomedix (United States)(US)Helix Biostructures (United States)
Publications by Year
Research Areas
Cancer Mechanisms and Therapy, Protein Kinase Regulation and GTPase Signaling, Melanoma and MAPK Pathways, Cancer-related Molecular Pathways, Ubiquitin and proteasome pathways
Most-Cited Works
- → Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition(2004)614 cited
- → Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice(1995)538 cited
- → A Farnesyltransferase Inhibitor Induces Tumor Regression in Transgenic Mice Harboring Multiple Oncogenic Mutations by Mediating Alterations in Both Cell Cycle Control and Apoptosis(1998)172 cited
- → Characterization of recombinant human farnesyl-protein transferase: Cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases(1993)137 cited
- → Discovery of a Novel Class of Dimeric Smac Mimetics as Potent IAP Antagonists Resulting in a Clinical Candidate for the Treatment of Cancer (AZD5582)(2013)113 cited
- → Genes for two herbicide-inducible cytochromes P-450 from Streptomyces griseolus(1990)